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Animal Health Research/動物の健康研究
Animal Health Research activities at AHB Japan are focused on the development and improvement of technology for diagnosis of animal disease, control of animal diseases, prevention of foreign animal diseases, safety of animal products and management of veterinary pharmaceutics to enhance animal productivity and ensure public health.
1. Research and development (R&D) management
– Development of long-term research plans in the field of Veterinary Science and Animal Quarantine
– Operation of Data-based (DB) management system for research projects and those products
– Strengthening of incentive programs that award excellence in research
– Expansion of domestic and international research collaboration
– Establishment of (OIE) certificated reference laboratory and ISO/IEC 17025
– Provide basic free service such as collection, deposit and distribution of biological material of animal pathogens
2. Research on the control of major animal diseases
– Research on the control of bacterial and viral diseases including Johne’s disease, classical swine fever (CSF), Foot-and-mouth disease(FMD), etc.
– Research on avian diseases including Newcastle disease (ND), fowl typhoid, etc.
– Development of technologies for rapid diagnosis of foreign animal diseases including rinderpest, etc.
– Research on vesicular diseases including swine vesicular disease, vesicular stomatitis and etc.
– Research on transmissible spongiform encephalopathies including BSE, CWD and Scrapie
– Research on emerging exotic disease including West Nile Fever, Bluetongue and etc.
– Research on aquatic animal disease including Edwardsiellosis, Aeromoniasis, etc.
– Research on the development and quality control for – veterinary pharmaceutics
– Research on enteric & respiratory disease and food-borne disease
– Research on mastitis and hygiene of raw milk
3. Research on the surveillance and control measures against zoonoses
– Establishment of long-term road map for research of major zoonoses
– National surveillance/ monitoring on TSEs, and major foreign animal diseases
– Research on emerging diseases including BSE, avian influenza, West nile disease, etc.
– Research on endemic disease including anthrax, tuberculosis, brucellosis, rabies etc.
– Research on the control of parasite, and tick-borne, and insect diseases including toxoplasmosis, etc.
– Research on the control of companion animal diseases including canine influenza virus etc.
4. Research and development of diagnostic methods, vaccines and therapeutic agents for the control of animal diseases using advanced biotechnology
– Development of DNA chip for differential diagnosis of – classical swine fever
– Development and application of Japanese encephalitis attenuated live vaccine
– Development of diagnostic technologies, vaccines, and antiviral agents against FMD
5. Research on the safety of food of animal origin
– Management of national residue programme (NRP) in food of animal origin
– Research on the evaluation of toxicity and risk assessment of toxic chemicals
– Development of analytical method and monitoring of hazardous chemicals (veterinary drugs, pesticides and environmental contaminants) in food of animal origin
– Research on pharmacodynamics and residue depletion for veterinary drugs
– Development of rapid immunological assay kits for veterinary drugs in foods of animal origin
– Research on multi-drug resistant bacteria and prevention of microorganism contamination
6. Technical assistance on the basis of research projects
– Rapid diagnosis and early response of newly emerging animal diseases
– Operation of reference laboratory and standardization of inspection methods to ensure safety of livestock product
– Development and distribution of diagnostic reagents and technical support for diagnosis standardization
– Technology distribution and education to provide solutions to problems faced in the field
7. Animal stem cell research and application
– Establishment of animal stem cell bank
– Use of animal stem cell to control livestock diseases and zoonosis
– Development of animal stem cell therapeutics to cure companion & leisure animal diseases
– Application of animal stem cell for drug discovery and toxicity
– Development of stem cell model for the screening of toxicity and therapeutic effect of chemicals
AHB Japanでの動物衛生研究活動は、動物疾病の診断、動物疾病の管理、外来動物疾病の予防、動物製品の安全性、および動物の生産性を高め、公衆衛生を確保するための動物用医薬品の管理のための技術の開発と改善に焦点を当てています。 。 1.研究開発（R＆D）管理 –獣医学および動物検疫の分野における長期研究計画の策定 –研究プロジェクトおよびそれらの製品のためのデータベース（DB）管理システムの運用 –研究の卓越性を授与するインセンティブプログラムの強化 –国内および国際的な研究協力の拡大 –（OIE）認定リファレンスラボおよびISO / IEC17025の設立 –動物病原体の生物学的物質の収集、預け入れ、配布などの基本的な無料サービスを提供する 2.主要な動物疾病の管理に関する研究 –ジョン病、豚コレラ（CSF）、口蹄疫（FMD）などの細菌性およびウイルス性疾患の管理に関する研究。 –ニューカッスル病（ND）、鶏腸チフスなどの鳥類の病気に関する研究。 –牛疫などの外来動物の病気を迅速に診断するための技術の開発。 –豚水疱病、水疱性口内炎などを含む水疱性疾患の研究。 – BSE、CWD、スクレイピーなどの伝達性海綿状脳症に関する研究 –ウエストナイル熱、ブルータングなどを含む新たなエキゾチックな病気に関する研究。 –エドワジエラ症、エアロモニア症などの水生動物の病気に関する研究。 –獣医薬剤学の開発と品質管理に関する研究 –腸および呼吸器疾患および食品媒介性疾患に関する研究 –生乳の乳房炎と衛生に関する研究 3.人獣共通感染症に対する監視および管理措置に関する研究 –主要な人獣共通感染症の研究のための長期ロードマップの確立 –TSEおよび主要な外国の動物の病気に関する全国的な監視/監視 – BSE、鳥インフルエンザ、ウエストナイル病などの新興感染症に関する研究。 –炭疽菌、結核、ブルセラ症、狂犬病などの風土病に関する研究。 –寄生虫、ダニ媒介性、およびトキソプラズマ症などの昆虫病の防除に関する研究。 –犬インフルエンザウイルスなどのコンパニオンアニマル病の管理に関する研究。
4.高度なバイオテクノロジーを使用して動物の病気を制御するための診断方法、ワクチン、治療薬の研究開発 –鑑別診断用のDNAチップの開発–豚コレラ –日本脳炎弱毒生ワクチンの開発と応用 – FMDに対する診断技術、ワクチン、および抗ウイルス剤の開発 5.動物由来食品の安全性に関する研究 –動物由来食品における国家残留プログラム（NRP）の管理 –毒性の評価と有毒化学物質のリスク評価に関する研究 –動物由来食品中の有害化学物質（動物用医薬品、農薬、環境汚染物質）の分析方法とモニタリングの開発 –動物用医薬品の薬力学と残留物枯渇に関する研究 –動物由来食品中の動物用医薬品用の迅速な免疫学的アッセイキットの開発 –多剤耐性菌と微生物汚染の防止に関する研究 6.研究プロジェクトに基づく技術支援 –新たに出現した動物の病気の迅速な診断と早期対応 –畜産物の安全性を確保するための参照研究所の運営と検査方法の標準化 –診断試薬の開発と配布、および診断標準化のための技術サポート –現場で直面する問題の解決策を提供するための技術の配布と教育 7.動物幹細胞の研究と応用 –動物幹細胞バンクの設立 –家畜の病気や人獣共通感染症を制御するための動物幹細胞の使用 –コンパニオンおよびレジャー動物の病気を治療するための動物幹細胞治療薬の開発 –創薬と毒性のための動物幹細胞の応用 –化学物質の毒性と治療効果をスクリーニングするための幹細胞モデルの開発
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